The WHO reiterated Friday there was “no adequate data” on switching Covid-19 vaccines between doses, after France mentioned under-55s who obtained an AstraZeneca first jab ought to get their second from a distinct vaccine.
The World Health Organization has referred to as for research on so-called mixing and matching between vaccines, however mentioned there was no complete knowledge to this point on which it may make any suggestions.
The UN well being company subsequently recommends that the identical product ought to be used for each doses.
In February, the WHO’s Strategic Advisory Group of Experts on Immunization (SAGE) issued its suggestions on how the AstraZeneca-Oxford vaccine ought to be used, WHO spokeswoman Margaret Harris instructed reporters.
“There is not adequate data to be able to say whether this is something that could be done,” she mentioned.
“So they have been recommending that at this stage, interchangeability of vaccines was not one thing that we may give a suggestion on.
“But they did make a analysis suggestion that this be studied, in order that we may perceive whether or not or not it was a method that might be used.”
Several medical trials are trying on the efficacy of mixing two varieties of vaccine.
Europe’s medicines regulator mentioned this week that the AstraZeneca vaccine may trigger very uncommon blood clots amongst some recipients, prompting a number of international locations to scale up restrictions on the jab.
France on Friday mentioned under-55s who obtained a primary injection of the AstraZeneca Covid-19 vaccine ought to be given a jab from a distinct producer for his or her second dose, in a ruling affecting 533,000 folks.
The Pfizer-BioNTech vaccine was the primary Covid-19 jab to obtain WHO’s inexperienced mild, on December 31 final yr.
The AstraZeneca-Oxford University was the second, on February 15, with SAGE having issued utilization suggestions 5 days earlier than.
That February 10 doc mentioned on switching between Covid-19 vaccines: “No knowledge can be found on the interchangeability of doses of this vaccine with different Covid-19 vaccines.
“It is currently recommended that the same product should be used for both doses. Recommendations may be updated as further information becomes available on interchangeability.”
Going ahead, the SAGE doc additionally advisable “interchangeability and ‘mix and match’ studies within and across Covid-19 vaccine platforms”.
On Wednesday, the WHO’s vaccine specialists mentioned a hyperlink between AstraZeneca’s Covid-19 jabs and blood clots was believable however unconfirmed, stressing that reported occurrences have been “very rare”.
“Based on current information, a causal relationship between the vaccine and the occurrence of blood clots with low platelets is considered plausible but is not confirmed,” the specialists mentioned.
A WHO spokesman added: “We imagine the benefit-risk steadiness could be very a lot in favour of the vaccine.
“Nothing has modified in our recommendation — which is to maintain vaccinating.”
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